题目:响应micromolds连续图案的水凝胶摘要:微型水凝胶已被证明是有益的多种应用,如组织工程和药物传递。一个关键方面,这些应用是空间组织实体的生物或化学化合物在水凝胶的微观结构。为了这个目的,顺序图案凝胶可用于任何空间生活材料组织模仿生物的复杂性或多个化工设计功能微粒用于药物递送。光刻方法是最常见的方式,但模式微型水凝胶光交联聚合物有限公司。到目前为止,常规微方法使用静态模具制造结构,限制由此产生的形状,可以生成。在此,我们描述一个动态的微成形技术制造利用连续图案水凝胶的微观结构该thermoresponsiveness聚(N -异丙基丙烯酰胺)—基micromolds。这些反应micromolds展出形状的变化,在温度变化,促进连续成型的微凝胶在不同温度。我们制造multicompartmental条纹,圆柱,和立方微封装荧光聚合物微球或不同的细胞类型。这些反应micromolds可以用来固定生活物资连续图案凝胶微观结构和化学物质这可能是有益的一系列应用程序的界面化学,材料科学与工程,和生物学。
《信息检索与利用》课程考核与实习报告 200 –200 学年第 学期 指导教师 学院、班级____________________ 姓名、学号______________________ 报告完成日期_____________ 总 成 绩_____________________ _ 说明:“课程考核与实习报告”为本课程考核形式,最迟请于课程结束后一周内完成。 提交形式:纸质文本以A4纸打印交给班长,由班长按学号整序后交给任课老师。 第一部分 基础知识题 共20分 请指出以下文献的出版类型(5分) (1)袁润,沙振江 大学生信息素质初级教程 镇江:江苏大学出版社,2007:188 (2)Diez, Fernando; Moriyon, R Solving mathematical exercises that involve symbolic Computing in Science and Engineering, v 6, n 1, January/February, 2004, p 81-84 (3)Fahrenthold, Eric PDiscrete Hamilton's equations for distributed property systems Proceedings of the American Control Conference, v 6, 2002, p 4960-4961 (4)Stereo active vision and peripheral optical flow: Computer vision applications of the wide-field human visual representation by Wagner, Robert Edward, PhD BOSTON UNIVERSITY, 2004, 142 pages (5)茹国军高级阳离子淀粉的生产方法[P]CN,1043135A1990-06-20 答:(1) (2) (3) (4) (5) 要了解某一课题的最新研究成果,可选择以下哪些类型的文献,请说明理由。(5分) ①图书 ②期刊 ③会议论文 ④学位论文 ⑤专利 ⑥标准 ⑦科技报告。 三、《中图法》的全称是什么?《中图法》分为几个基本大类?分类号是由什么组成的?你所学专业的相关图书应该分在哪个大类?(5分) 答: 四、IPC的中文全称是什么?它用于什么类型文献的分类?它的结构形式如何?(5分) 答: 第二部分 实习报告 (共80分) 课题检索说明: 实习时,围绕选定的课题进行检索与报告。检索年限:近5年的相关文献。如果文献量太少,可以放宽检索年限。 本报告中的题录要求:中文文献包含文献的外部特征和内容特征;外文文献包含文献的外部特征。 检索式包括检索词、逻辑组配符号等,如有其他检索限定请一一注明。 一、选题(15分) 1.检索课题名称 中文: ___________________________________________ 英文:____________________________________________ 所涉及的学科领域 3.关键词或主题词 中文: __________________________________ 英文 4.检索式 中文: ___________________________________________ 英文:____________________________________________ 二、期刊论文数据库检索(20分) 从中国学术期刊全文库、万方数据库资源、维普资源信息系统等中文全文数据库中选择2种数据库进行检索 数据库1______________________________________ 年限___________ 其他限定条件_________________ 检索式___________________________________________________ 检出篇数___________ 题录(1篇)___________________________________________________ _______________________________________________________________ 数据库2 ______________________ 年限_________其他限定条件_________________ 检索式___________________________________________________ 检出篇数________ 题录(1篇)__________________________________________________ _______________________________________________________________ 2、根据课题所属学科,选择本馆外文数据库中的任意2个数据库进行检索 数据库1________________ 检索年限_________ 其他限定条件_________________ 检出篇数_________ 检索式__________________________________________________________ 题录(1篇)___________________________________________________________ 数据库2_____________________________ 检索年限 __________其他限定条件_________________ 检出篇数______ 检索式___________________________________________ 题录(1篇)__________________________________________________________ 三、 网络信息检索(6分) 利用搜索引擎检索与本课题有关的信息。 检索工具名称(如yahoo!、Google等):_____ ___ 检索过程: 检出记录数: 摘录1条简要信息: 2、 利用搜索引擎检索本专业重要中、英文网站各一个(写出网址、该网站简要介绍) (1)__________________________________________________________________ ___________________________________________________________________ (2)__________________________________________________________________ ___________________________________________________________________ 四、本专业中外文重要学术期刊(4分) 请查出你所学学科领域内的国内核心期刊,找出其中两种核心期刊编辑部的地点、电话、邮编、E-mail 地址. (1)______________________________________________________________ (2)______________________________________________________________ 五.联合目录检索(4分) 选择你所学学科领域内的一种国内核心期刊,利用中科院全国期刊联合目录数据库()查找该期刊在国内有哪些图书馆有收藏。 刊物名称: 馆藏情况: 六、特种文献检索(16分) 1.从本馆中外文学位论文数据库中(中外文库各选一个)检索有关文献。 数据库1______________________________________ 年限___________其他限定条件_________________ 检索式___________________________________________________ 检出篇数___________ 题录(1篇)___________________________________________________ _______________________________________________________________ 数据库2 ______________________ 年限_________其他限定条件_________________ 检索式___________________________________________________ 检出篇数________ 题录(1篇)__________________________________________________ _______________________________________________________________ 请利用中华人民共和国国家知识产权局 查找有关专利。要求拷贝专利文献的书目数据(申请号、申请日、公开号、公开日、授权公告号、授权公告日、发明人、申请人、专利权人、专利题目、IPC 号有限权项等),尤其要注意其法律状态数据。 七、从本课题的检索中你获得了哪些新知识?(10分) __________________________________________________________________ __________________________________________________________________ 八、对本课程的意见、建议和收获(5分) __________________________________________________________________ __________________________________________________________________
蒽环类—甲醛轭合物与其靶向前药 甲醛使口蹄疫病毒失活。制备安全疫苗的条件。 咔唑与甲醛的反应。N-羟甲基咔唑在酸性条件下的反应。 利用甲醛歧化酶与甲醇氧化体系,以甲醇为原料生产甲酸盐(酯) 哌啶与甲醛的催化反应机理研究 利用三聚 氰胺—甲醛树脂对亚氨基甲酸基进行硫化(这个感觉不太顺,原文如此吗?)
疏水缔合型聚合物P(AMTA)溶液性质的研究疏水缔合型水溶性聚合物是指在聚合物亲水性大分子链上带有少量疏水基团的一类水溶性聚合物。在聚合物水溶液中,疏水基团之间由于憎水作用而发生聚集,使大分子链产生分子内和分子间缔合。在临界缔合质量分数以上,形成分子间缔合为主的超分子结构,增大了流体力学体积,故具有较好的增黏性。在盐溶液中,由于小分子电解质的加入增加了溶液极性,使疏水缔合作用增强,表现出明显的抗盐性质。 疏水缔合型水溶性高分子很难合成,且不易表征,把疏水部分连接到水溶性聚合物链上,一般采用胶束共聚合或者使用具有表面活性的大单体进行共聚,胶束聚合需要在体系中加入大量的表面活性剂,这就增加了后处理过程的复杂性。利用表面大单体共聚合,需要事先合成大单体,这方面的技术也有相当大的难度。作者采用丙烯酸十四酯作为疏水单体,直接用沉淀聚合法制备疏水缔合型聚合物P(AM/TA)共聚物,从而使共聚反应及其产物的后处理过程较为简单易行。并用凯达尔定氮法表征共聚物的组成,研究共聚物的溶液性能和对苯丙乳液的增稠性。 1实验 1.1试剂 丙烯酰胺(AM),质量分数不少于985%,根据文献提供的方法提纯;N,N-甲基甲酰胺(DMF),分析纯;甲醇、氯化钠,化学纯;丙烯酸十四酯(TA),实验室自制;苯丙乳液由福建省福州树脂有限公司提供。 1.2P(AM/TA)共聚物的合成 称取一定量的AM和TA单体,用DMF溶解,转入三颈瓶中,通氮除氧。升温至80℃,加入引发剂反应4h,过滤,产物用甲醇洗涤多次,以除去未反应的单体。40℃真空干燥至恒重。 1.3分析测试 凯达尔定氮法测定共聚物的组成。用乌氏黏度计测定共聚物溶液特性黏度[η],测试温度为(30±O1)℃。聚合物溶液表观黏度用NDJ-I型旋转黏度计测定。 2结果与讨论 2.1共聚物稀溶液性质不同疏水基团摩尔分数的P(AM/TA)共聚物在蒸馏水和w(NaCl)=5%的溶液中的特性黏度[η]值列于表1。 聚合物的[η]正比于溶液中大分子线团的流体力学体积,因而能反应大分子线团收敛、卷曲的程度。从表1可知,随共聚物的TA链节摩尔分数的增加,其水溶液的[η]值逐渐减小,在w(NaCl)=5%的溶液中也是持续减小。这是因为在稀溶液中,疏水基团缔合以分子内缔合为主,随着TA摩尔分数的增加,分子内缔合增强,导致分子链卷曲。在盐溶液中,由于离子电荷的作用,使疏水链节分子内缔合力增强,分子链收缩,因而[η]值也持续下降。 2.2疏水基团TA摩尔分数对聚合物溶液黏度的影响 图1和图2分别表示P(AM/TA)系列共聚物及PAM在蒸馏水和w(NaCl)=5%的溶液中表观黏度与聚合物质量分数的关系曲线。PAM溶液黏度随其质量分数的增加而平缓上升,而疏水共聚物溶液的质量分数为3O%~4O%时其黏度急剧增加,表明疏水基团聚集而导致分子间缔合,形成了物理交联网络。此时共聚物溶液的质量分数即是临界缔合的质量分数。如图1所示,随TA摩尔分数增加,共聚物溶液的黏度显著增加。当疏水基团摩尔分数较高时,其溶液黏度随质量分数增加的速度更快,共聚物的临界缔合质量分数降低。如图2所示,加入Nacl溶液后,溶液表观黏度有较大提高,如质量分数为O%的P(AM/TA)-1 5聚合物溶液在20℃,转速为6r/min时,黏度达OmPs,而在水溶液中的黏度只有374mPa·s。不同TA摩尔分数的聚合物的质量分数均较其在纯水中低。Hydrophobically associating polymer P (AMTA) the nature of the study solution Hydrophobically associating water-soluble polymer is the hydrophilic polymer with a small amount of macromolecular chain hydrophobic group of a class of water-soluble Aqueous solution in the polymer, the hydrophobic groups and between the role as a result of hydrophobic aggregation occurred, so that large molecules have a molecular chain and inter-molecular Associating the critical mass fraction of the above, the formation of intermolecular association based supramolecular structure, increases the volume of fluid mechanics, it has good by In salt solution, because of the addition of small molecule electrolyte solution increased polarity, so that co-operation with enhanced hydrophobic association, shows that the nature of the Hydrophobically associating water-soluble polymer-based synthesis is difficult and not easily characterized, in part to hydrophobic chains connected to the water-soluble polymer, the general use of micellar copolymerization, or the use of the large surfactant monomer to copolymerization, polymer micelles need in the system by adding a large number of surface-active agent, which, after an increase of the complexity of the The use of the surface monomer copolymerization, the need for prior synthesis of large monomer, this technology also has considerable Author tetradecyl acrylate used as a hydrophobic monomer, the direct use of precipitation polymerization Preparation of hydrophobically associating polymer P (AM / TA) copolymers, so that the product of copolymerization and post-processing is more simple and easy And characterization of nitrogen determination Kedar copolymer composition, study the solution properties of copolymers of styrene-acrylic emulsion and of the 1 Experimental 1 Reagents Acrylamide (AM), the mass fraction of not less than 985 percent, according to documents provided by purification methods; N, N-dimethylformamide (DMF),分析纯; methanol, sodium chloride, chemical pure; acrylic 10 four acetate (TA), laboratory-made; styrene-acrylic emulsion resin from Fuzhou in Fujian Province L 2P (AM / TA) Copolymer Check that a certain amount of monomer AM and TA, using DMF dissolved into three-neck bottle, pass oxygen Warming to 80 ℃, reaction by adding initiator 4h, filtering, washing the product several times with methanol to remove unreacted 40 ℃ vacuum drying to constant 3 Analysis and Testing Determination of nitrogen Kedar will be the composition of Determination of intrinsic viscosity with copolymer solution viscosity [η], the test temperature (30 ± O1) ℃ Apparent viscosity of polymer solution with NDJ-I-type rotary viscometer 2 Results and Discussion 1 Dilute Solution Properties of Copolymers of different mole fraction of hydrophobic groups of the P (AM / TA) copolymers in distilled water, and w (NaCl) = 5% of the solution intrinsic viscosity [η] values listed in Table Polymer [η] is proportional to the solution of the fluid dynamics of macromolecular coil volume, which can respond to the convergence coil macromolecules, the degree of We can see from Table 1, with the copolymer chain of the TA increase in mole fraction, the aqueous solution of [η] value decreases in w (NaCl) = 5% of the solution is continued to This is because in dilute solution, the hydrophobic group to intramolecular association based association, with the mole fraction of the increase in TA, to enhance intramolecular association, resulting in the molecular chain In salt solution, because of the role of ionic charge, so that intramolecular hydrophobic chain to enter into force enhancement, molecular chain contraction, so [η] value continued to TA hydrophobic group 2 mole fraction of polymer solution viscosity on the impact of figures 1 and 2, respectively, P (AM / TA) series of copolymers and PAM in distilled water, and w (NaCl) = 5% in the apparent viscosity of the solution and the relationship between the mass fraction of polymer PAM solution viscosity with the increase of mass fraction of gentle rise, and the hydrophobic copolymer solution for the mass fraction of 3O% ~ 4O%, when a sharp increase in viscosity, indicating that aggregation of hydrophobic groups and lead to intermolecular association, forming a physical crosslinking网络 At this point the mass fraction of copolymer solution that is the critical mass fraction of the As shown in Figure 1, with the mole fraction of TA increased, the viscosity of copolymer solution increased When the mole fraction of hydrophobic groups is high, the solution viscosity increases with the mass fraction of the faster, the critical aggregation copolymer mass fraction As shown in Figure 2, by adding Nacl solution, the solution has greatly enhanced apparent viscosity, such as the mass fraction of O% for the P (AM / TA) -1 5 polymer solution at 20 ℃, rotation speed 6r/min , the viscosity of OmPs, and viscosity in aqueous solution only 374mPa TA different mole fraction of the mass fraction of polymer in water were