Pick to: along with the development of society, how safe, effective and rational drug use has caused social strong These years about the adverse drug reactions (adverse drug reaction event shall ADR) reports and discussion has many, has caused the attention and To the requirements of clinical medicine not just watched it can not can heal, and pay more attention to the disease in time, using the drugs shall ADR appear as little as Rational drug use and reasonable treatment always exist, it is not only a both old and new topic, also is the pharmacy workers the eternal Pharmacy mission is to serve people as the center, based in clinical pharmacy, and promote the clinical science use, its core is to guarantee the safety of clinical treatment Based on reference, talk about how common adverse drug reaction and drug safety problems Keywords: security; Reasonable; Adverse reaction