肿瘤的综述性论文

做肿瘤的一定都知道Robert A Weinberg，他在2000年发表在Cell上的《The hallmarks of cancer》现在的引用次数已经超过10000次，几乎做肿瘤的每一个人都会看这么一篇经典文章。在2011年3月4日，他又在Cell上继续发表了题为《Hallmarks of Cancer: The Next Generation》的文章，将肿瘤的六种武器扩充到十种武器。我觉得这又堪称是肿瘤学研究中经典与必读文章了。SummaryThe hallmarks of cancer comprise six biological capabilities acquired during the multistep development of human The hallmarks constitute an organizing principle for rationalizing the complexities of neoplastic They include sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating invasion and Underlying these hallmarks are genome instability, which generates the genetic diversity that expedites their acquisition, and inflammation, which fosters multiple hallmark Conceptual progress in the last decade has added two emerging hallmarks of potential generality to this list—reprogramming of energy metabolism and evading immune In addition to cancer cells, tumors exhibit another dimension of complexity: they contain a repertoire of recruited, ostensibly normal cells that contribute to the acquisition of hallmark traits by creating the “tumor ” Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human 只能说这么多了、具体我也不太了解、并且对你的问题也没太搞清楚、希望可以帮到你！

《肿瘤学杂志》为面向全国的学术类科技期刊，创办于1971年8月，原名《浙江肿瘤通讯》，1995年获准公开出版发行并更名为《浙江肿瘤》， 2001年改为现名。由浙江省肿瘤医院和浙江省抗癌协会主办，为中国抗癌协会系列杂志。及时反映我国肿瘤学术研究领域的新技术、新成果和新进展，主要刊登肿瘤临床与基础类学术论文，主要栏目有述评、论著、综述、经验交流、短篇报道等。

CA-A CANCER JOURNAL FOR CLINICIANS，顶级期刊期刊名字 CA-A CANCER JOURNAL FOR CLINICIANS期刊ISSN 0007-92352015-2016最新影响因子 5是否OA开放访问 No通讯方式 WILEY-BLACKWELL PUBLISHING, INC, COMMERCE PLACE, 350 MAIN ST, MALDEN, USA, MA, 02148涉及的研究方向 医学-肿瘤学出版国家或地区 UNITED STATES出版周期 Bimonthly出版年份 1950年文章数 24